Anticancer and antioxidative effects of micronized zeolite clinoptilolite
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Micronized zeolite clinoptilolite (MZ) reduced the metabolic rate of cancer cells and increased binding of 4-hydroxynonenal (HNE) to albumin in vitro. It selectively reduced generation of HNE in vivo in tumor stroma after Doxorubicin treatment leaving onset of lipid peroxidation intact in malignant cells.
Combined treatment with Doxorubicin and MZ resulted in strong reduction of the pulmonary metastasis count increasing anticancer effects of Doxorubicin.
CONCLUSION: Interference of MZ with lipid peroxidation might explain some of the beneficial effects of this particular zeolite in combined cancer therapy.
